CD68 Antibody

h1 class=titleCD68 Antibody/h1
div id=node-1450 class=node ntype-antibodiesRabbit Polyclonal
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h4Catalog Number/h4
pstrong250594/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Data and Images/h4
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pspan class=inline lefta href=http://www.abbiotec.com/image/cd68-staining-mouse-lungimg class=image image-medium title=CD68 staining in mouse lung: Paraffin-embedded mouse cancerous lung is stained with CD68 Antibody (Cat. No. 250594) used at a 1:50 dilution. alt=CD68 staining in mouse lung: Paraffin-embedded mouse cancerous lung is stained with CD68 Antibody (Cat. No. 250594) used at a 1:50 dilution. width=300 height=255 src=http://www.abbiotec.com/files/images/250594_lung.medium.jpg //aspan style=width: 298px class=captionstrongCD68 staining in mouse lung: /strongParaffin-embedded mouse cancerous lung is stained with CD68 Antibody (Cat. No. 250594) used at a 1:50 dilution./span/span/p
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h4Description/h4
pThe CD68 antigen is involved in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 binds to tissue- and organ-specific lectins and selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane helps macrophages to move over selectin-bearing substrates and other cells. CD68 is highly expressed by blood monocytes and tissue macrophages as well as many tumor cell lines promoting binding to selectins on vascular endothelium facilitating dissemination to secondary sites./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pMacrosialin; Gp110; CD68/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P31996P31996/abr /
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h4Clonality/h4
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h4Antigen/h4
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pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse CD68./p
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h4Application Notes/h4
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pE: 1:500-1:1,000/p
pWB: 1:200-1:500/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; :M | R/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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