Catalog Number252257 Unit0.1 mg IsotypeRabbit Ig ApplicationsE, WB, IHC Species reactivityM, R Format
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4. Antibody was purified by Protein-G affinity chromatography.
| DescriptionThe CD68 antigen is involved in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 binds to tissue- and organ-specific lectins and selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane helps macrophages to move over selectin-bearing substrates and other cells. CD68 is highly expressed by blood monocytes and tissue macrophages as well as many tumor cell lines promoting binding to selectins on vascular endothelium facilitating dissemination to secondary sites. Alternate NamesMacrosialin; Gp110; CD68 Accession No.Antigen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse CD68.
Application Notes
E: 1:500-1:1,000 WB: 1:200-1:500 IHC: 1:200-1:500
Storage
Store at -20°C. Product is guaranteed 6 months from the date of shipment. |