CD62E (HI62E) Antibody

h1 class=titleCD62E (HI62E) Antibody/h1
div id=node-1795 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250976/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pCD62E antibody recognizes a 115KD type I transmembrane glycoprotein, E-selectin, also called endothelial-leucocyte adhesion molecule-1 (ELAM-1). CD62E is expressed on cytokine (such as IL-2, TNF-alpha;) stimulated endothelium in vitro, transiently expressed on endothelium at sites of acute inflammation in vivo, and is also expressed on endothelium in chronic inflammatory lesions of skin and synovium. Non-inflammatory expression of CD62E has been observed in endothelium in skin, placenta and bone marrow. CD62E mediates leucocyte rolling on activated endothelium at inflammatory sites and may also support tumor cell adhesion during hematogenous metastasis, and plays a role in angiogenesis. Sialyl Lewis X (CD15s) and PSGL-1 (CD162) act as ligands for CD62E./p
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h4Alternate Names/h4
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h4Accession No./h4
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h4Clonality/h4
pHI62E/p
h4Antigen/h4
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h4Application Notes/h4
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pPurified antibody is suitable for immunohistochemistry with acetone-fixed and frozen sections.E: 1:500-1:1,000/p
pFACS: 1:200-1:1,000/p
pIHC: 1:200-1:500/p
pE:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment/p
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