CD6 (HI210) Antibody

h1 class=titleCD6 (HI210) Antibody/h1
div id=node-1807 class=node ntype-antibodiesMouse Monoclonal, APC-conjugated, FITC-conjugated
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h4Catalog Number/h4
pstrong250995/strong/p
h4Unit/h4
pstrong2 ml/strong/p
h4Format/h4
pEach vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pCD6 antibody recognizes a 100-130 KD typeâ… single-chain transmembrane glycoprotein. CD6 is expressed at low levels on immature thymocytes, and at high levels on mature thymocytes. CD6 is also expressed at high levels on peripheral blood T cells and at low levels on most peripheral blood B cells. High levels of CD6 are present in T-cell malignancies and certain B-cell malignancies including B-CLL. CD6 not only is expressed on all CD5+ B-CLL, but also on CD5- B-CLL, suggesting a broader distribution of CD6 than CD5 in B-cell malignancies. It is found recently CD6 is also on a minor subset of myeloid malignancies. CD6 functions as an adhesion molecule as well as a co stimulatory molecule for T cell activation. The ligand for CD6 is CD166./p
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h4Product Citations/h4
pnbsp;/p
pSchlossman S., L. Bloumsell, W. Gilks, et al., eds. 1995. Leucocyte Typing Ⅴ: White Cell Differentiation Antigens. P：246nbsp;nbsp; Oxford University Press, New York./p
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h4Recommended Products/h4
pbr /
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h4Alternate Names/h4
pT-cell differentiation antigen CD6; T12; TP120; CD6 antigen; CD6/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P30203P30203/abr /
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h4Clonality/h4
pHI210/p
h4Antigen/h4
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h4Application Notes/h4
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pFACS with whole blood: 100 mu;l blood + 20 mu;l antibody; FACS with cells: 10E6 cells + 20 mu;l antibody. E: 1:500-1:1,000/p
pFACS: 1:200-1:1,000/p
pIHC: 1:200-1:500/p
pIF:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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