CD55 (HI55a) Antibody

The CD55 (HI55a) antibody recognizes the human cell surface antigen CD55 (complement decay-accelerating factor, DAF), a GPI linked molecule widely expressed on human peripheral blood granulocyte, monocyte, and some lymphocytes and erythrocytes. CD55 recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups during their activation. This interaction interferes with the conversion of C2 and factor B to amplify the complement cascade. CD55 polymorphism is responsible for the Cromer blood group system.