CD45RA (HI100) Antibody

h1 class=titleCD45RA (HI100) Antibody/h1
div id=node-1824 class=node ntype-antibodiesFITC-conjugated, Mouse Monoclonal
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h4Catalog Number/h4
pstrong251026/strong/p
h4Unit/h4
pstrong2 ml/strong/p
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Format/h4
pEach vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pCD45RA antibody recognizes the 205/220KD isoform of leukocyte common antigens expressed on about 40-50% of peripheral CD4+ T cells, 50% of peripheral CD8+ T cells and on a portion of B cells and monocytes. Studies have shown that expression of different isoform is characteristic of differentiated subset of hematopoietic cells (for instance CD45RA on naiuml;ve/ resting T cells and CD45RD on memory/ activated T cells; CD45RA on medullary thymocytes and CD45RD on cortical thymocytes). It is also reported that the pattern of 87% of B-ALL is CD45RA+/ CD45RO-, 70% of T-ALL is CD45RA-/ CD45RD+ and 78% of B-ALL is CD45RA+/ CD45RO+./p
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h4Product Citations/h4
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pShen DC ; Chen Z ; Bai JF; et al ; 1991. Properties and preliminary application of three monoclonal antibodies of non-lineage antigens- CD45, CD45R and CD53. J. Monoclonal Antibody. 7(1):53/p
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h4Recommended Products/h4
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h4Alternate Names/h4
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h4Accession No./h4
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h4Clonality/h4
pHI100/p
h4Antigen/h4
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h4Application Notes/h4
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pFACS with whole blood: 100 mu;l blood + 20 mu;l antibody; FACS with cells: 10E6 cells + 20 mu;l antibody. E: 1:500-1:1,000/p
pFACS: 1:200-1:1,000/p
pIHC: 1:200-1:500/p
pIF:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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