CD45RA (HI100) Antibody

h1 class=titleCD45RA (HI100) Antibody/h1
div id=node-1211 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250970/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pThe CD45RA (HI100) antibody recognizes the 205/220-kDa isoform of leukocyte common antigen expressed on 40-50% peripheral CD4+ T cells, 50% peripheral CD8+ T cells and a portion of B cells and monocytes. Studies have shown that expression of different isoforms is characteristic of differentiated subset of hematopoietic cells (for instance CD45RA on naiuml;ve/ resting T cells and CD45RD on memory/ activated T cells; CD45RA on medullary thymocytes and CD45RD on cortical thymocytes). It is also reported that the pattern of 87% of B-ALL is CD45RA+/ CD45RO-, 70% of T-ALL is CD45RA-/ CD45RD+ and 78% of B-ALL is CD45RA+/ CD45RO+./p
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h4Product Citations/h4
pnbsp;/p
pShen DC, Chen Z, Bai JF, et al. 1991. J. Monoclonal Antibody. 7(1):53/p
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h4Recommended Products/h4
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h4Alternate Names/h4
pLeukocyte common antigen; L-CA; T200; CD45 antigen; PTPRC; Protein tyrosine phosphatase receptor type C/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P08575P08575/abr /
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h4Clonality/h4
pHI100/p
h4Antigen/h4
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h4Application Notes/h4
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pPurified antibody is suitable for immunohistochemistry with acetone-fixed frozen and formalin-fixed paraffin sections. E: 1:500-1:1,000; FACS: 1:200-1:1,000; IHC: 1:200-1:500/p
pnbsp;strongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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