CD41 (platelet), mouse anti human, clone 96.2C1

Osteopontin is an extensively phosphorylated and glycosylated 278-residue chemokine. It interacts with alpha-V/beta-3, CD44 and other adhesion structures. Biologically, it appears to form part of the mineralized matrix and is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10. Immunohistological detection and plasma levels are correlated with poor outcome in neoplastic diseases. The antibody has been generated by repeated immunizations of rabbits with purified mouse osteopontin. Application: ELISA, Western blots, IHC (f,p)