CD3E (4E2) Antibody

CD3E (T-cell surface glycoprotein CD3 epsilon chain) is a member of the T-cell receptor-CD3 complex. CD3-epsilon polypeptide together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The epsilon polypeptide plays an essential role in T-cell development.