CD33 (HIM3-4) Antibody

h1 class=titleCD33 (HIM3-4) Antibody/h1
div id=node-1817 class=node ntype-antibodiesFITC-conjugated, Mouse Monoclonal
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h4Catalog Number/h4
pstrong251015/strong/p
h4Unit/h4
pstrong2 ml/strong/p
h4Format/h4
pEach vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pCD33 antibody recognizes a 67 KD type I transmembrane glycoprotein expressed mainly on monocytes, granulocytes (weakly), myeloid progenitors and mast cells, but not on lymphocytes, platelets, erythrocytes and hematopoietic stem cells. CD33 antigen is a useful marker for the diagnosis of non lymphoblastic leukemias and also for distinguishing myelogenous leukemia cells from lymphoid leukemia cells. The CD33 antigen is earlier expressed in the cytoplasm (cyCD33) than the expression on the cell membrane (mCD33) of the myeloblasts. It is more valuable using cyCD33 and cyCD13 to diagnose leukemia of AML-M0 (as the CD13 antigen is also earlier expressed in the cytoplasm (cyCD13) than the expression on the cell membrane (mCD13) of the myeloblasts). The CD33 antigen functions as an adhesion molecule./p
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h4Product Citations/h4
pnbsp;/p
pTadamitsu K., K.Hitoshi, A.E.G.Kr.van dem Borne, et al., eds. 1997. Leucocyte Typing â…¥: White Cell Differentiation Antigens. Garland Publishing, Inc., New York.nbsp;/p
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h4Recommended Products/h4
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h4Alternate Names/h4
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h4Accession No./h4
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h4Clonality/h4
pHIM3-4/p
h4Antigen/h4
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h4Application Notes/h4
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pFACS with whole blood: 100 mu;l blood + 20 mu;l antibody; FACS with cells: 10E6 cells + 20 mu;l antibody. E: 1:500-1:1,000/p
pFACS: 1:200-1:1,000/p
pIHC: 1:200-1:500/p
pIF:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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