CD32 (Fc gamma receptor type 2, isoforms A, B and C), mouse anti human, clone 2E1

UniProt: Q96LB1. MRGPRX2 or cortistatin receptor is a 330 amino acid protein that belongs to the G-protein coupled receptor 1 family. Mas-related G-protein coupled receptors (Mrgprs) represent a large family of orphan receptors specifically expressed in small-diameter nociceptive primary sensory neurons. Physiological functions include mediation of itch or regulation of persistent pathological pain. Cortistatin-14, which is involved in sleep regulation, locomotor activity, and cortical function, seems to be a high potency ligand at this receptor. Also, the multifunctional antibacterial protein LL-37 (H-7298) has been shown to activate cells presumably through MRGPRX2. Application: IHC (p)