CD31 (N-term) Antibody

h1 class=titleCD31 (N-term) Antibody/h1
div id=node-1448 class=node ntype-antibodiesRabbit Polyclonal
div class=contentstyle type=text/css
!--
h4 {
margin: 30px 0 0 0;
padding: 0;
border-top: 1px solid #bbb;
background: #f8f8f8;
}
--/style
div class=product-table
table border=0 cellspacing=10 cellpadding=0 width=100%
tbody
tr
td valign=top width=50%
h4Catalog Number/h4
pstrong250589/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4
pnbsp;/p
Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
pnbsp;/p
h4Data and Images/h4
div class=field field-type-text field-field-data-img-01
div class=field-items
div class=field-item
pspan class=inline lefta href=http://www.abbiotec.com/image/cd31-staining-mouse-melanoma-and-rat-fat-tissueimg class=image image-medium title=CD31 staining in mouse melanoma and rat fat tissue: Vascular endothelial cells in paraffin-embedded mouse melanoma (top) and rat fat tissue (bottom) are stained with CD31 (N-term) Antibody (Cat. No. 250589) used at a 1:200 dilution. alt=CD31 staining in mouse melanoma and rat fat tissue: Vascular endothelial cells in paraffin-embedded mouse melanoma (top) and rat fat tissue (bottom) are stained with CD31 (N-term) Antibody (Cat. No. 250589) used at a 1:200 dilution. width=150 height=300 src=http://www.abbiotec.com/files/images/250589_fat_and_melanoma.medium.jpg //aspan style=width: 148px class=captionstrongCD31 staining in mouse melanoma and rat fat tissue: /strongVascular endothelial cells in paraffin-embedded mouse melanoma (top) and rat fat tissue (bottom) are stained with CD31 (N-term) Antibody (Cat. No. 250589) used at a 1:200 dilution./span/span/p
/div
/div
/div
/td
td valign=top
h4Description/h4
pCD31 (PECAM1) is a member of the immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils, and particular T-cell subsets. CD31 is also a major constituent of the endothelial cell intercellular junction, where up to an estimated 1 million molecules are concentrated. Because of this cellular expression pattern, CD31 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis, and integrin activation. Ig superfamily members are known to mediate cell adhesion, or antigen recognition, e.g. immunoglobulins, T-cell receptors, and MHC molecules. In addition, a subgroup comprising 30 members characterized by the presence of one or more immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within their cytoplasmic domain has also been recognized. CD31, which has 6 ITIMs within its cytoplasmic domain, is a member of this subfamily./p
br style=clear: both /
br style=clear: both /
h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pbr /
nbsp;/p
h4Alternate Names/h4
pPlatelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; CPIIA'; CD31 antigen; PECAM1/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P16284P16284/abr /
nbsp;/p
h4Clonality/h4
pnbsp;/p
h4Antigen/h4
pnbsp;/p
pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD31./p
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pE: 1:500-1:1,000/p
pWB: 1:200-1:500/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; :H | M | R | Other/p
pnbsp;/p
h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
/td
/tr
/tbody
/table
/div
/div
/div