CD29 (HI29a) Antibody

h1 class=titleCD29 (HI29a) Antibody/h1
div id=node-1746 class=node ntype-antibodiesMouse Monoclonal, PE-conjugated
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h4Catalog Number/h4
pstrong251070/strong/p
h4Unit/h4
pstrong2 ml/strong/p
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Format/h4
pEach vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pCD29 antibody recognizes the 130-kDa transmembrane glycoprotein integrin beta;1 subunit which is the common beta;1 chain of the very late antigen (VLA) forming a non-covalent heterodimeric complex with several integrins alpha; subunits that are receptors for extracellular matrix proteins such as collagen, fibronectin and osteopontin. CD29 has a broad tissue distribution including lymphocytes, monocytes, platelets, fibroblasts, and endothelial cells, whereas it is weakly expressed in granulocytes and absent in erythrocytes. CD29 is an important adhesion molecule involved in cell-cell and cell-extracellular matrix interactions. CD29 plays a critical role in the functional activity of lymphocytes by influencing cellular migration patterns as well as by transducing intracellular signals that influence lymphocyte function./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pIntegrin beta-1; Fibronectin receptor subunit beta; Integrin VLA-4 subunit beta; CD29 antigen; ITGB1; FNRB; MDF2; MSK12/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P05556P05556/abr /
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h4Clonality/h4
pHI29a/p
h4Antigen/h4
pnbsp;/p
h4Application Notes/h4
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pFACS with whole blood: 100 mu;l blood + 20 mu;l antibody; FACS with cells: 10E6 cells + 20 mu;l antibody./p
pIF: 1:200-1:1,000/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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