CD272 Antibody

Catalog Number

252250

Unit

0.1 mg

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4. Antibody was purified by Protein-G affinity chromatography.

Description

B- and T-lymphocyte attenuator (BTLA or CD272) is a lymphocyte inhibitory receptor which inhibits lymphocytes during the immune response. CD272 is not expressed by naïve T-cells but is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. CD272 is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1).

Alternate Names

B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD272; BTLA

Accession No.

Q7Z6A9

 

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD272.

Application Notes

E: 1:500-1:1,000

WB: 1:100-1:500

IHC: 1:100-1:500

Storage

Store at -20°C. Product is guaranteed 6 months from the date of shipment.