CD2 (HIT11) Antibody

h1 class=titleCD2 (HIT11) Antibody/h1
div id=node-1806 class=node ntype-antibodiesMouse Monoclonal, FITC-conjugated
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h4Catalog Number/h4
pstrong250989/strong/p
h4Unit/h4
pstrong2 ml/strong/p
h4Format/h4
pEach vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pThe CD2 (HIT11) antibody recognizes a 50-kDa type-I single-chain transmembrane glycoprotein called LFA-2 (lymphocyte function associated antigen-2) or sheep red blood cell (SRBC) receptor. The CD2 antigen is expressed on 70-80% of peripheral blood lymphocytes and 80%-90% of thymocytes and NK cells. The primary ligand for CD2 is CD58 (LFA-3) despite binding to CD48, CD59 and CD15. The CD2 antigen plays a role in T cell signaling and in lymphocyte adhesion, and is an alternative pathway of T cell activation. There are two forms of CD2, a membrane form on cell surface and a soluble form in serum./p
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h4Product Citations/h4
pnbsp;/p
pSchlossman S., L. Bloumsell, W. Gilks, et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York./p
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h4Recommended Products/h4
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h4Alternate Names/h4
pT-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; LFA-2; LFA-3 receptor; erythrocyte receptor; rosette receptor; CD2 antigen; CD2; SRBC/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.ch/uniprot/P06729P06729/abr /
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h4Clonality/h4
pHIT11/p
h4Antigen/h4
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h4Application Notes/h4
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pFACS with whole blood: 100 mu;l blood + 20 mu;l antibody; FACS with cells: 10E6 cells + 20 mu;l antibody. E: 1:500-1:1,000/p
pFACS: 1:200-1:1,000/p
pIHC: 1:200-1:500/p
pIF:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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