CD19 (HIB19) Antibody

h1 class=titleCD19 (HIB19) Antibody/h1
div id=node-1781 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250951/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pThe CD19 antibody recognizes a 95 kDa type-I transmembrane glycoprotein which is restricted to B cell antigen. CD19 antigen is expressed on normal and neoplastic B cells and also in some bone marrow cells. CD19 expression by B progenitor cells is presumably at late pro-B or early pre-B stages around the time of Ig heavy chain rearrangement. Expression persists during all stages of B cell maturation and is lost on terminal differentiation to plasma cells. CD19 antigen is also found on the follicular dendritic cells and the early cells of myelomonocytic lineage but not on normal T cells, NK cells, monocytes, granulocytes, erythrocytes and platelets. In normal peripheral blood, 8-20% of lymphocytes express CD19 antigen. CD19 antigen plays a role in regulating B cell proliferation./p
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h4Product Citations/h4
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pYang XF, Shen DC., Guan Q., et al., HIM35: a monoclonal antibody synergistically stimulating hematopoiesis. Tissue Antigens. 42(4):387/p
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h4Recommended Products/h4
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h4Alternate Names/h4
pFavaloro, E.J., Bradstock, K.F., Kabral, A., Grimsley, P., Zowtyi, H. and Zola, H. (1988). Further characterization of myeloid antigens ('gp160,95', 'gp150' and 'gp567'): Investigation of epitope heterogenetity and non-haemopoietic distribution using panels of monoclonal antibodies belonging to CD-11b, CD-13 and CD-33. British Journal of Hematology, 69: 163-171./p
h4Accession No./h4
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h4Clonality/h4
pHIB19/p
h4Antigen/h4
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h4Application Notes/h4
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pPurified antibody is suitable for immunohistochemistry with acetone-fixed and frozen sections./p
pE: 1:500-1:1,000/p
pFACS: 1:200-1:1,000/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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