CD19 Antibody

h1 class=titleCD19 Antibody/h1
div id=node-1892 class=node ntype-antibodiesRabbit Polyclonal, HRP-conjugated
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h4Catalog Number/h4
pstrong252248/strong/p
h4Unit/h4
pstrong0.1 mg /strong/p
h4Isotype/h4
Rabbit Ig
h4Applications/h4
E, WB, IHC
h4Species reactivity/h4
H, M, R
h4Format/h4
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pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pCD19 is a 95 kDa type-I transmembrane glycoprotein which is restricted to B cell antigen. CD19 antigen is expressed on normal and neoplastic B cells and also in some bone marrow cells. CD19 expression by B progenitor cells is presumably at late pro-B or early pre-B stages around the time of Ig heavy chain rearrangement. Expression persists during all stages of B cell maturation and is lost on terminal differentiation to plasma cells. CD19 antigen is also found on the follicular dendritic cells and the early cells of myelomonocytic lineage but not on normal T cells, NK cells, monocytes, granulocytes, erythrocytes and platelets. In normal peripheral blood, 8-20% of lymphocytes express CD19 antigen. CD19 antigen plays a role in regulating B cell proliferation./p
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h4Alternate Names/h4
pB-lymphocyte antigen CD19; Differentiation antigen CD19; B-lymphocyte surface antigen B4; Leu-12; CD19 antigen; CD19/p
h4Accession No./h4
pa class=accession-link href=http://www.expasy.ch/uniprot/P15391 target=_blankP15391/abr /
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h4Antigen/h4
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pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD-19./p
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h4Application Notes/h4
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pE: 1:500-1:1,000/p
pWB: 1:200-1:500/p
pIHC: 1:200-1:500/p
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h4Storage/h4
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pStore at -20deg;C. Product is guaranteed 6 months from the date of shipment./p
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