CD181 Antibody

Antibodies

貨號 Cat. No.
251385
規格 Size
0.1 mg
品牌 Brand
Abbiotec
Application 應用
ELISA 、 IHC 、 WB
Reactivity
B 、 Canine 、 Human 、 Mouse 、 Rat

Description

C-X-C chemokine receptor type 1 (CXC-R1, CD181) is a receptor to interleukin-8, which is a powerful neutrophil chemotactic factor. Binding of IL-8 to CD181 causes activation of neutrophils. This response is mediated via a G-protein cascade that activates a phosphatidylinositol-calcium second messenger system. CD181 binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

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