CD181 Antibody
Antibodies
- 貨號 Cat. No.
- 251385
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 IHC 、 WB
- Reactivity
- B 、 Canine 、 Human 、 Mouse 、 Rat
Description
C-X-C chemokine receptor type 1 (CXC-R1, CD181) is a receptor to interleukin-8, which is a powerful neutrophil chemotactic factor. Binding of IL-8 to CD181 causes activation of neutrophils. This response is mediated via a G-protein cascade that activates a phosphatidylinositol-calcium second messenger system. CD181 binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.