CD147 Antibody

Catalog Number

250583

Unit

0.1 mg

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Description

CD147 (Basigin or Leukocyte activation antigen M6) plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. CD147 stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPs). CD147 is only present in vascular endothelium in non-neoplastic regions of the brain. Although present in tumor cells, CD147 is not expressed in proliferating blood vessels in malignant gliomas.

Alternate Names

Basigin; Leukocyte activation antigen M6; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; 5F7; Tumor cell-derived collagenase stimulatory factor; TCSF; OK blood group antigen; CD147; BSG

Accession No.

P35613

 

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD147.

Application Notes

E: 1:500-1:1,000

WB: 1:200-1:500

IHC: 1:200-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.