Cathepsin S Inhibitor Screening Kit (Fluorometric)

Alternate Name :

Tag Line :

Only kit on the market to screen Cathepsin S inhibitors

Storage Conditions: -20°C

Shelf life: 12 months

Summary :

• Detection method- Fluorescence (Ex/Em = 400/505 nm)
• Applications- Screen/study/characterize potential inhibitors of Cathepsin S.

Detection Method: Fluorescence (Ex/Em = 400/505 nm)

Features & Benefits:

• Simple & convenient
• High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin S
• Cathepsin S inhibitor, Z-FF-FMK is included in the kit

Description:

Cathepsin S (CTSS, EC 3.4.22.27) is a lysosomal cysteine proteinase that is suggested to participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Biovision’s Cathepsin S Inhibitor Screening Kit utilizes the ability of Cathepsin S to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin S inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This high-throughput adaptable assay kit is simple, sensitive, and rapid tool to screen the potential inhibitors of Cathepsin S.