Cathepsin L Inhibitor Screening Kit (Fluorometric)

Alternate Name :

Tag Line :

Only kit on the market to screen Cathepsin L inhibitors

Storage Conditions: -20°C

Shelf life: 12 months

Summary :

• Detection method- Fluorescence (Ex/Em = 400/505 nm)
• Applications- Screen/study/characterize potential inhibitors of Cathepsin L

Detection Method: Fluorescence (Ex/Em = 400/505 nm)

Features & Benefits:

• Convenient & Rapid
• High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin L
• Cathepsin L inhibitor, FF-FMK is included in the kit

Description:

Cathepsin L (CTSL, EC 3.4.22.15) is a lysosomal cysteine protease that is implicated in protein degradation, arthritis, apoptosis, and cancer. Biovision’s Cathepsin L Inhibitor Screening Kit utilizes the ability of active Cathepsin L to cleave the synthetic AFC-based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin L inhibitor, the cleavage of this substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize potential inhibitors of Cathepsin L.