Cathepsin G, Human Neutrophil

Alternate Names / Synonyms: Cathepsin G

Gene Symbol: N/A

Accession #: N/A

Gene ID: N/A

Gene Source: N/A

Recombinant Host: Human Neutrophil

Appearance: Lyophilized protein

Physical Form: Salt- free lyophilized solid

Molecular Weight: 23.5 kDa

Purity by SDS-PAGE: ≥95%

Purity by HPLC: N/A

Endotoxin Level: N/A

Biological Activity: 2 to 4 units per mg protein. One unit of activity is defined as the amount of enzyme that hydrolyzes one micromole of Suc-Ala-Ala-Pro-Phe-pNA (1 mM) per minute at 25°C in 160 mM Tris-HCl, pH 7.4, with 1.6 M NaCl.

Reconstitution: Deionized water

Storage Temp.: -20°C

Shipping: Gel pack

Background Information: Cathepsin G is a serine protease secreted by activated neutrophils that play a role in the inflammatory response. This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.

Handling: Centrifuge the vial prior to opening.