Cathepsin G Activity Colorimetric Assay Kit

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Storage Conditions: -20°C

Shelf life: 6-12 months

Summary :

• Detection method- Absorbance (405 nm)
• Species reactivity- Mammalian
• Kit size- 100 assays
• Applications- Detects alternative proteolytic enzymes such as the lysosomal cathepsin G proteases that can initiate or propagate proapoptotic signals.

Detection Method:

Features & Benefits:

• Simple one-step procedure; takes only 1 hours
• Fast, robust and convenient
• Cathepsin-G assay is straightforward, and can be adapted to 96-well plate assays.

Description:

Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. The protein is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In BioVision’s Cathepasin G Activity assay Kit, Cathepsin G will cleave the substrate and release the dye group, pNA (4-Nitroaniline), which can be detect at 405 nm. In presence of the Cathepsin G specific inhibitor, the cleavage will be stopped. The kit provides a rapid, simple, sensitive, and reliable test suitable for the activity of Cathepsin G.