CaspGLOW™ Red Active Caspase-8 Staining Kit

Alternate Name :

Tag Line :

Detects activated Caspase-8 by FACS, FL or plate reader

Storage Conditions: -20°C

Shelf life: 6-12 months

Summary :

• Detection method- Fluorescence microscopy, fluorescence plate reader (Ex/Em = 540/570 nm) and Flow cytometry
• Species reactivity- Mammalian
• Kit size- Convenient sizes (25 and 100 assays)
• Applications- Detection of activated caspase-8 in living cells.

Detection Method:

Features & Benefits:

• Simple one-step procedure; takes only 1-2 hours
• Fast and convenient
• The fluorescence label allows detection of activated caspase-8 in apoptotic cells

Description:

Activation of caspases plays a central role in apoptosis. The CaspGLOWTM Red Active Caspase-8 Staining Kit provides a convenient means for detecting activated caspase-8 in living cells. The assay utilizes a caspase-8 inhibitor IETD-FMK conjugated to sulfo-rhodamine (Red-IETD-FMK) as the fluorescent marker. Red-IETD-FMK is cell permeable, nontoxic, and irreversibly binds to activated caspase-8 in apoptotic cells.