Caspase-6 (Active) Antibody
- 貨號 Cat. No.
- 3156-100
- 規格 Size
- 100 µg
Description
pstrongAntibody Target :/strongCaspase-6 (Active)/p
pstrongHost: Rabbit /strong/p
pstrongAntibody Type: Polyclonal /strong/p
pstrongIsotype: Rabbit IgG /strong/p
pstrongAntibody Form: Affinity Purified Antibody /strong/p
pstrongImmunogen Sequence: Synthetic peptide surrounding amino acids mapping to the C-terminus of the large fragment of human caspase-6 /strong/p
pstrongAccession#: AAH00305 /strong/p
pstrongGene ID: 839 /strong/p
pstrongAppearance: Colorless liquid /strong/p
pstrongConcentration: 0.5 mg/ml /strong/p
pstrongFormulation: 100 micro;g (0.5 mg/ml) affinity purified rabbit anti-active caspase-6 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. /strong/p
pstrongPurification: Affinity purified /strong/p
pstrongSpecies Reactivity: hu/ms/rt /strong/p
pstrongApplication: WB /strong/p
pstrongApplication amp; Usage: Western blotting (0.5-4 micro;g/ml) and immunofluorescence. However, the optimal conditions should be determined individually. The antibody detects the large subunit (18 kDa) of the active caspase-6. The antibody does not recognize other caspases. /strong/p
pstrongStorage Temp.: -20 deg;C /strong/p
pstrongShipping : gel pack /strong/p
pstrongShelf Life: 12 months /strong/p
pstrongHandling: The antibody solution should be gently mixed before use. /strong/p
pstrongBrief Background Descriptions: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with caspase-3, caspase-6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors Bcl-2 and Bcl-xL. Caspase-6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A./strong/p
pstrongHost: Rabbit /strong/p
pstrongAntibody Type: Polyclonal /strong/p
pstrongIsotype: Rabbit IgG /strong/p
pstrongAntibody Form: Affinity Purified Antibody /strong/p
pstrongImmunogen Sequence: Synthetic peptide surrounding amino acids mapping to the C-terminus of the large fragment of human caspase-6 /strong/p
pstrongAccession#: AAH00305 /strong/p
pstrongGene ID: 839 /strong/p
pstrongAppearance: Colorless liquid /strong/p
pstrongConcentration: 0.5 mg/ml /strong/p
pstrongFormulation: 100 micro;g (0.5 mg/ml) affinity purified rabbit anti-active caspase-6 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. /strong/p
pstrongPurification: Affinity purified /strong/p
pstrongSpecies Reactivity: hu/ms/rt /strong/p
pstrongApplication: WB /strong/p
pstrongApplication amp; Usage: Western blotting (0.5-4 micro;g/ml) and immunofluorescence. However, the optimal conditions should be determined individually. The antibody detects the large subunit (18 kDa) of the active caspase-6. The antibody does not recognize other caspases. /strong/p
pstrongStorage Temp.: -20 deg;C /strong/p
pstrongShipping : gel pack /strong/p
pstrongShelf Life: 12 months /strong/p
pstrongHandling: The antibody solution should be gently mixed before use. /strong/p
pstrongBrief Background Descriptions: Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with caspase-3, caspase-6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors Bcl-2 and Bcl-xL. Caspase-6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A./strong/p