Caspase-3 (Human) ELISA Kit

Alternate Name :

Tag Line :

An Sandwich ELISA kit for the quantitative measurement of human Caspase-3 in human serum, plasma, culture supernatants and other biological fluids

Storage Conditions: 4°C

Shelf life: 6 months

Summary :

• Detection method- Absorbance (450 nm)
• Species reactivity- Human
• Application- quantitative measurement of Caspase-3 in human serum, plasma, tissue homogenates and other biological fluids.

Detection Method: Absorbance (450 nm)

Features & Benefits:

Easy, convenient and time-saving method to measure the level of Caspase-3 in human serum, plasma, tissue homogenates, culture supernatants and other biological fluids.
Detection Range: 0.313-20 ng/ml
Sensitivity: < 0.188 ng/ml

Description:

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. BioVision’s Caspase-3 ELISA kit is a sandwich ELISA assay for the quantitative measurement of human Caspase-3 in serum, plasma and cell culture supernatants. The density of color is proportional to the amount of Caspase-3 captured from the samples.