Caspase-10 Antibody

h1 class=titleCaspase-10 Antibody/h1
div id=node-1171 class=node ntype-antibodiesRabbit Polyclonal
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h4Catalog Number/h4
pstrong250571/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pCaspase 10 is involved in the activation cascade of caspases responsible for apoptosis execution. It cleaves and activates caspase-3, -4, -6, -7, -8, and -9 and is recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. Caspase-10 participates in the granzyme B apoptotic pathways, and hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pCaspase 10; CASP-10; ICE-like apoptotic protease 4; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; CASP10; MCH4/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/Q92851Q92851/abr /
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h4Clonality/h4
pnbsp;/p
h4Antigen/h4
pnbsp;/p
pKLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human caspase-10./p
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h4Application Notes/h4
pnbsp;/p
pE: 1:500-1:1,000/p
pWB: 1:100-1:500/p
pIHC: 1:200-1:500/p
pIP:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H | M | R/p
pnbsp;/p
h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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