Canertinib (CI-1033, PD-183805)
- 貨號 Cat. No.
- 1617-50
- 規格 Size
- 50 mg
Description
50 mg. Purity >99%. CAS# 289499-45-2. Canertinib (CI-1033, PD183805) effectively inhibits the growth of esophageal squamous cell carcinoma which co-expresses both EGFR and HER2 with the inhibition of phosphorylation of both MAPK and AKT. CI-1033 was highly potent against EGFR (IC50 0.8 nM), HER-2 (IC50 19 nM) and ErbB-4 (IC50 7 nM). Soluble in DMSO. Store cool and dry at -20C. Protect from light.