CaMKII Substrate Peptide
- 貨號 Cat. No.
- 350007
- 規格 Size
- 1 mg
- 品牌 Brand
- Abbiotec
Description
h1 class=titleCaMKII Substrate Peptide/h1
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h4Catalog Number/h4
pstrong350007/strong/p
h4Unit/h4
pstrong1 mg/strong/p
h4Price/h4
pstrong$69.00/strong/p
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pnbsp;/p
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h4Description/h4
pThis peptide is a substrate (Km = 7.5 micro;M) for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the residues 1-10 of the glycogen synthase containing a phosphorylation site at Ser-7 within the R-X-X-S/T consensus site and is amidated at the C-terminus end. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. Phosphorylation of the substrate is calcium and calmodulin dependent./p
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h4Format/h4
pnbsp;/p
pEach vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt./p
pnbsp;/p
h4Data and Images/h4
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h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pbr /
a href=http://www.abbiotec.com/peptides/camkii-%5B290-309%5D-inhibitory-peptide%C2%A0350007 CaMKII [290-309] Inhibitory Peptidenbsp;/abr /
nbsp;/p
h4Alternate Names/h4
pSubstrate: Glycogen synthase; GYS1; GYS; Enzyme: Calcium/calmodulin-dependent protein kinase type II alpha chain; CaM-kinase II alpha chain; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2A; CAMKA; KIAA0968/p
h4Accession No./h4
pa class=accession-link href=http://au.expasy.org/uniprot/P13834 target=_blankP13834/abr /
a class=accession-link href=http://au.expasy.org/uniprot/Q9UQM7 target=_blankQ9UQM7/abr /
nbsp;/p
h4MW/h4
p1045.1 g/mol/p
h4Sequence/h4
pPro-Leu-Ser-Arg-Thr-Leu-Ser-Val-Ser-Ser-NH2 or PLSRTLSVSS-NH2/p
h4Composition/h4
pnbsp;/p
pC44H80N18O15/p
pnbsp;/p
h4Purity/h4
pPurity gt; 95% by HPLC/p
h4Solubility/h4
pDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile./p
h4Storage/h4
pStore at -20deg;C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20deg;C./p
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div class=product-table
table cellspacing=10 cellpadding=0 width=100% border=0
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h4Catalog Number/h4
pstrong350007/strong/p
h4Unit/h4
pstrong1 mg/strong/p
h4Price/h4
pstrong$69.00/strong/p
/td
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pnbsp;/p
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div class=descriptionpad
h4Description/h4
pThis peptide is a substrate (Km = 7.5 micro;M) for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the residues 1-10 of the glycogen synthase containing a phosphorylation site at Ser-7 within the R-X-X-S/T consensus site and is amidated at the C-terminus end. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. Phosphorylation of the substrate is calcium and calmodulin dependent./p
/div
table cellspacing=10 cellpadding=0 width=100% border=0
tbody
tr
td valign=top width=50%
h4Format/h4
pnbsp;/p
pEach vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt./p
pnbsp;/p
h4Data and Images/h4
/td
td valign=top
h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pbr /
a href=http://www.abbiotec.com/peptides/camkii-%5B290-309%5D-inhibitory-peptide%C2%A0350007 CaMKII [290-309] Inhibitory Peptidenbsp;/abr /
nbsp;/p
h4Alternate Names/h4
pSubstrate: Glycogen synthase; GYS1; GYS; Enzyme: Calcium/calmodulin-dependent protein kinase type II alpha chain; CaM-kinase II alpha chain; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2A; CAMKA; KIAA0968/p
h4Accession No./h4
pa class=accession-link href=http://au.expasy.org/uniprot/P13834 target=_blankP13834/abr /
a class=accession-link href=http://au.expasy.org/uniprot/Q9UQM7 target=_blankQ9UQM7/abr /
nbsp;/p
h4MW/h4
p1045.1 g/mol/p
h4Sequence/h4
pPro-Leu-Ser-Arg-Thr-Leu-Ser-Val-Ser-Ser-NH2 or PLSRTLSVSS-NH2/p
h4Composition/h4
pnbsp;/p
pC44H80N18O15/p
pnbsp;/p
h4Purity/h4
pPurity gt; 95% by HPLC/p
h4Solubility/h4
pDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile./p
h4Storage/h4
pStore at -20deg;C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20deg;C./p
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