CaMKII [290-309] Inhibitory Peptide

h1 class=titleCaMKII [290-309] Inhibitory Peptidenbsp;/h1
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h4Catalog Number/h4
pstrong350006/strong/p
h4Unit/h4
pstrong1 mg/strong/p
h4Price/h4
pstrong$139.00/strong/p
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pnbsp;/p
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h4Description/h4
pThis peptide is a potent calmodulin antagonist and an inhibitor for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the residues 290-309 within the calmodulin-binding domain of human CaMKII alpha. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. This peptide inhibits CaMKII activationnbsp; by blocking calmodulin binding to CaMKII./p
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h4Format/h4
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pEach vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt./p
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h4Data and Images/h4
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h4Product Citations/h4
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h4Recommended Products/h4
pbr /
a href=http://www.abbiotec.com/peptides/CaMKII-Substrate-Peptide350007 CaMKII Substrate Peptide/abr /
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h4Alternate Names/h4
pCalcium/calmodulin-dependent protein kinase type II alpha chain; CaM-kinase II alpha chain; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2A; CAMKA; KIAA0968/p
h4Accession No./h4
pa class=accession-link href=http://au.expasy.org/uniprot/Q9UQM7 target=_blankQ9UQM7/abr /
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h4MW/h4
p2273.9 g/mol/p
h4Sequence/h4
pLeu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala or LKKFNARRKLKGAILTTMLA/p
h4Composition/h4
pnbsp;/p
pC103H185N31O24S1/p
pnbsp;/p
h4Purity/h4
pPurity gt; 95% by HPLC/p
h4Solubility/h4
pDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile./p
h4Storage/h4
pStore at -20deg;C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20deg;C./p
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