Calreticulin Antibody
- 貨號 Cat. No.
- 3077-100
- 規格 Size
- 100 µg
Description
pstrongAntibody Target :/strongCalreticulin/p
pstrongHost: Rabbit /strong/p
pstrongAntibody Type: Polyclonal /strong/p
pstrongIsotype: Rabbit IgG /strong/p
pstrongAntibody Form: Affinity Purified Antibody /strong/p
pstrongImmunogen Sequence: Synthetic peptide mapping to the C-terminus of Human Calreticulin /strong/p
pstrongAccession#: P27797 /strong/p
pstrongGene ID: 811 /strong/p
pstrongAppearance: Colorless liquid /strong/p
pstrongConcentration: 0.2 mg/ml /strong/p
pstrongFormulation: 100 micro;g (200 micro;g/ml) protein A purified antibody in PBS containing 30% glycerol, 0.5 mg/ml BSA, and 0.01% thimerosal. /strong/p
pstrongPurification: Affinity purified /strong/p
pstrongSpecies Reactivity: hu/ms/rt /strong/p
pstrongApplication: WB/IHC /strong/p
pstrongApplication amp; Usage: Western blot analysis (0.5-4 micro;g/ml) and in Immunohistochemistry (10-20 micro;g/ml). However, the optimal conditions should be determined individually. /strong/p
pstrongStorage Temp.: -20 deg;C /strong/p
pstrongShipping : gel pack /strong/p
pstrongShelf Life: 12 months /strong/p
pstrongHandling: The antibody solution should be gently mixed before use. /strong/p
pstrongBrief Background Descriptions: Calreticulin is a calcium binding protein found in abundance in the endoplasmic reticulum and the sarcoplasmic reticulum. Like many other ER proteins, it has the conserved ER retention KDEL (Lys-Asp-Glu-Leu) sequence at its C-terminus. Calreticulin has also been detected in the nucleus and nuclear envelop. Recent studies suggest that this soluble ER protein has a multifunctional role as it appears to be involved in calcium storage and regulation as well as having a molecular chaperone activity. Studies also suggest its involvement in certain autoimmune diseases. Consistence with its multiple functions the calreticulin molecule appears to have a zonal character. The protein has both high and low affinity calcium binding sites. /strong/p
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pstrongHost: Rabbit /strong/p
pstrongAntibody Type: Polyclonal /strong/p
pstrongIsotype: Rabbit IgG /strong/p
pstrongAntibody Form: Affinity Purified Antibody /strong/p
pstrongImmunogen Sequence: Synthetic peptide mapping to the C-terminus of Human Calreticulin /strong/p
pstrongAccession#: P27797 /strong/p
pstrongGene ID: 811 /strong/p
pstrongAppearance: Colorless liquid /strong/p
pstrongConcentration: 0.2 mg/ml /strong/p
pstrongFormulation: 100 micro;g (200 micro;g/ml) protein A purified antibody in PBS containing 30% glycerol, 0.5 mg/ml BSA, and 0.01% thimerosal. /strong/p
pstrongPurification: Affinity purified /strong/p
pstrongSpecies Reactivity: hu/ms/rt /strong/p
pstrongApplication: WB/IHC /strong/p
pstrongApplication amp; Usage: Western blot analysis (0.5-4 micro;g/ml) and in Immunohistochemistry (10-20 micro;g/ml). However, the optimal conditions should be determined individually. /strong/p
pstrongStorage Temp.: -20 deg;C /strong/p
pstrongShipping : gel pack /strong/p
pstrongShelf Life: 12 months /strong/p
pstrongHandling: The antibody solution should be gently mixed before use. /strong/p
pstrongBrief Background Descriptions: Calreticulin is a calcium binding protein found in abundance in the endoplasmic reticulum and the sarcoplasmic reticulum. Like many other ER proteins, it has the conserved ER retention KDEL (Lys-Asp-Glu-Leu) sequence at its C-terminus. Calreticulin has also been detected in the nucleus and nuclear envelop. Recent studies suggest that this soluble ER protein has a multifunctional role as it appears to be involved in calcium storage and regulation as well as having a molecular chaperone activity. Studies also suggest its involvement in certain autoimmune diseases. Consistence with its multiple functions the calreticulin molecule appears to have a zonal character. The protein has both high and low affinity calcium binding sites. /strong/p
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