Calreticulin Antibody
- 貨號 Cat. No.
- 3076-100
- 規格 Size
- 100 µg
Description
pstrongfont size=2
pfont size=2Antibody Target :Calreticulin /font/p
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pHost: Mouse/p
pAntibody Type: Monoclonal/p
pIsotype: Mouse IgG1/p
pAntibody Form: Affinity Purified Antibody/p
pImmunogen Sequence: Calreticulin-Maltose binding fusion protein/p
pAccession#: P27797/p
pGene ID: 811/p
pAppearance: Colorless liquid/p
pConcentration: 0.2 mg/ml/p
pFormulation: 100 micro;g (200 micro;g/ml) protein A purified antibody in PBS containing 30% glycerol, 0.5 mg/ml BSA, and 0.01% thimerosal./p
pPurification: Affinity purified/p
pSpecies Reactivity: hu/ms/rt/p
pApplication: WB/IHC/p
pApplication amp; Usage: Western blot analysis (0.5-4 micro;g/ml). However, the optimal conditions should be determined individually. Other applications have not been tested./p
pStorage Temp.: -20 deg;C/p
pShipping : gel pack/p
pShelf Life: 12 months/p
pHandling: The antibody solution should be gently mixed before use./p
pBrief Background Descriptions: Calreticulin is a calcium binding protein found in abundance in the endoplasmic reticulum and the sarcoplasmic reticulum. Like many other ER proteins, it has the conserved ER retention KDEL (Lys-Asp-Glu-Leu) sequence at its C-terminus. Calreticulin has also been detected in the nucleus and nuclear envelop. Recent studies suggest that this soluble ER protein has a multifunctional role as it appears to be involved in calcium storage and regulation as well as having a molecular chaperone activity. Studies also suggest its involvement in certain autoimmune diseases. Consistence with its multiple functions the calreticulin molecule appears to have a zonal character. The protein has both high and low affinity calcium binding sites./p
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pfont size=2Antibody Target :Calreticulin /font/p
/font/strongfont size=2
pHost: Mouse/p
pAntibody Type: Monoclonal/p
pIsotype: Mouse IgG1/p
pAntibody Form: Affinity Purified Antibody/p
pImmunogen Sequence: Calreticulin-Maltose binding fusion protein/p
pAccession#: P27797/p
pGene ID: 811/p
pAppearance: Colorless liquid/p
pConcentration: 0.2 mg/ml/p
pFormulation: 100 micro;g (200 micro;g/ml) protein A purified antibody in PBS containing 30% glycerol, 0.5 mg/ml BSA, and 0.01% thimerosal./p
pPurification: Affinity purified/p
pSpecies Reactivity: hu/ms/rt/p
pApplication: WB/IHC/p
pApplication amp; Usage: Western blot analysis (0.5-4 micro;g/ml). However, the optimal conditions should be determined individually. Other applications have not been tested./p
pStorage Temp.: -20 deg;C/p
pShipping : gel pack/p
pShelf Life: 12 months/p
pHandling: The antibody solution should be gently mixed before use./p
pBrief Background Descriptions: Calreticulin is a calcium binding protein found in abundance in the endoplasmic reticulum and the sarcoplasmic reticulum. Like many other ER proteins, it has the conserved ER retention KDEL (Lys-Asp-Glu-Leu) sequence at its C-terminus. Calreticulin has also been detected in the nucleus and nuclear envelop. Recent studies suggest that this soluble ER protein has a multifunctional role as it appears to be involved in calcium storage and regulation as well as having a molecular chaperone activity. Studies also suggest its involvement in certain autoimmune diseases. Consistence with its multiple functions the calreticulin molecule appears to have a zonal character. The protein has both high and low affinity calcium binding sites./p
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