Calpain 5 Polyclonal Antibody
- 貨號 Cat. No.
- 3375-100
- 規格 Size
- 100 ul
Description
pbHOST:/b Rabbit/p
pbIMMUNOGEN:/b Synthetic peptide mapping to domain II of human Calpain-5 large subunit/p
pbFORMULATION: /b100 ?l peptide affinity purified rabbit polyclonal anti-calpain-5 antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal/p
pbSPECIES REACTIVITY: /bhuman, mouse, rat/p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles. DESCRIPTION: Calpains are cytosolic, calcium-dependent, cysteine proteases that are ubiquitously expressed in mammalian and avian tissues. Calpain-1 and 2 consist of a common small subunit and a large variable subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF-hand domain IV. Calpain-5 is an intracellular calcium-dependent cysteine protease, which lacks the EF-hand calcium-binding motif of domain IV./p
pbSPECIFICITY: /bThe anti-calpain-5 antibody recognizes the 73 kDa and 58 kDa of Calpain-5, as well as several smaller cleavage products. It does not cross-react with other calpains./p
pbAPPLICATION: /bThe antibody can be used for Western blotting at 1:500-2000 dilutions. However, the optimal concentrations should be determined individually. USAGE:/p
pbFor Research Use Only. Not to be used in human. /b/p
pbIMMUNOGEN:/b Synthetic peptide mapping to domain II of human Calpain-5 large subunit/p
pbFORMULATION: /b100 ?l peptide affinity purified rabbit polyclonal anti-calpain-5 antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal/p
pbSPECIES REACTIVITY: /bhuman, mouse, rat/p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles. DESCRIPTION: Calpains are cytosolic, calcium-dependent, cysteine proteases that are ubiquitously expressed in mammalian and avian tissues. Calpain-1 and 2 consist of a common small subunit and a large variable subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF-hand domain IV. Calpain-5 is an intracellular calcium-dependent cysteine protease, which lacks the EF-hand calcium-binding motif of domain IV./p
pbSPECIFICITY: /bThe anti-calpain-5 antibody recognizes the 73 kDa and 58 kDa of Calpain-5, as well as several smaller cleavage products. It does not cross-react with other calpains./p
pbAPPLICATION: /bThe antibody can be used for Western blotting at 1:500-2000 dilutions. However, the optimal concentrations should be determined individually. USAGE:/p
pbFor Research Use Only. Not to be used in human. /b/p