C9 Complement (22) Antibody

h1 class=titleC9 Complement (22) Antibody/h1
div id=node-411 class=node ntype-antibodiesMouse Monoclonal
div class=contentstyle type=text/css
!--
h4 {
margin: 30px 0 0 0;
padding: 0;
border-top: 1px solid #bbb;
background: #f8f8f8;
}
--/style
div class=product-table
table border=0 cellspacing=10 cellpadding=0 width=100%
tbody
tr
td valign=top width=50%
h4Catalog Number/h4
pstrong250215/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
h4
pnbsp;/p
Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
pnbsp;/p
h4Data and Images/h4
/td
td valign=top
h4Description/h4
pComplement factor C9 is a 71-kDa single-chain ellipsoid a-globular molecule of 558 amino acids including a leader sequence of 20 amino acids. C9 bind the C5b8 complex on membranes and have an unique property in forming tubular structures containing between 12 and 18 monomers, closely resembling the membrane attack complex (MAC). Primary site of synthesis is hepatocytes, secondary sites are monocytes, fibroblasts and glial cells. The normal level of C9 in plasma is 60 micro;g/mL, and up regulated from hepatocytes by IFN-g.nbsp; This antibody is specific for complement factor C9./p
br style=clear: both /
br style=clear: both /
h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/c9-complement-%2853%29-antibody250216 C9 Complement (53) Antibody/abr /
nbsp;/p
h4Alternate Names/h4
pComplement factor C9/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P02748P02748/abr /
nbsp;/p
h4Clonality/h4
p22/p
h4Antigen/h4
pnbsp;/p
pComplement factor C9/p
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pProduct Cat. No. 250215 recognizes C9 in human serum diluted 1:50 in Tris buffer (20 mM Tris-base, 1 mM MgCl2, 1 mM CaCl2 and 140 mM NaCl) and incubated for 2 hours at 37deg;C using a human IgM coated (10 micro;g/mL overnight at 4deg;C, blocked with PBS 7.2 + 1% BSA for 1 hour) ELISA plate./p
pE: 1:30,000/p
pWB: 1:100-1:500/p
pstrongReacts with/strongnbsp; :H/p
pnbsp;/p
h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
/td
/tr
/tbody
/table
/div
/div
/div