C5b-9 Complement Antibody

h1 class=titleC5b-9 Complement Antibody/h1
div id=node-155 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250201/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography./p
pnbsp;/p
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h4Description/h4
pThis antibody recognizes the C5b-9 complement components, also named the terminal complement complex (TCC) that consists of the C5b, C6, C7, C8 and C9 components. The antibody specifically binds to a neoepitope exposed on C9 component upon complex formation in both membrane-bound (MAC) and fluid phase (SC5b-9) complexes. The antibody can be used for detecting C5b-9 in ELISA and immunohistocytology. The neoepitope is destroyed upon complex disruption during a western blot procedure./p
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h4Product Citations/h4
pnbsp;/p
pMollnes, TE et al. 1985. Scand J Immunol. 22(2): 183-95/p
pnbsp;/p
h4Recommended Products/h4
pa href=http://www.abbiotec.com/antibodies/C1-Inhibitor-Antibody250122 C1 Inhibitor Antibody/abr /
a href=http://www.abbiotec.com/antibodies/C3-Complement-Antibody250121 C3 Complement Antibody/abr /
a href=http://www.abbiotec.com/antibodies/C4-Complement-Antibody250123 C4 Complement Antibody/abr /
a href=http://www.abbiotec.com/antibodies/Anti-mouse-IgG-Antibody250137 Anti-mouse IgG Antibody/abr /
nbsp;/p
h4Alternate Names/h4
pTerminal complement complex; TCC; C5b; C6; C7; C8; C9; Complement component/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://au.expasy.org/uniprot/P02748P02748/abr /
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h4Clonality/h4
paE11/p
h4Antigen/h4
pnbsp;/p
pMembrane extract of detergent-lysed erythrocytes/p
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pThis antibody recognizes human C5b-9, also called the terminal complement complex (TCC) made of C5b, C6, C7, C8 and C9. The antibody is directed against a neoepitope exposed in C9 upon TCC complex formation. The antibody also reacts with porcine and equine TCC./p
pE:Use at an assay dependent concentration/p
pIHC:Use at an assay dependent concentration/p
pnbsp;strongReacts with/strongnbsp; :H | Other/p
pnbsp;/p
h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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