C5 Complement (12F3) Antibody

C5 is part of the membrane attack complex (MAC) of the complement system. C5 is split into C5a and C5b by the C5 convertases from the classical and the alternative complement pathway and the C5b fragment initiates the assembly of the terminal MAC (C5b-C9). The molecular mass of C5 is 190 kDa. This antibody is specific for human C5. No reaction is seen with plasma from patients deficient in C5.