C5 Complement (11F6) Antibody

h1 class=titleC5 Complement (11F6) Antibody/h1
div id=node-502 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250302/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pC5 is part of the membrane attack complex (MAC) of the complement system. C5 is split into C5anbsp;and C5b by the C5 convertases from the classical and the alternative complement pathway and the C5b fragment initiates the assembly of the terminal MAC (C5b-C9). The molecular mass of C5 is 190 kDa. This antibody is specific for human C5. No reaction is seen with plasma from patients deficient in C5./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pComplement component C5; Complement component 5 preprotein/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/NP_00172NP_00172/abr /
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h4Clonality/h4
p11F6/p
h4Antigen/h4
pnbsp;/p
pC5 isolated from human plasma/p
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h4Application Notes/h4
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pProduct Cat. No. 250302 reacts strongly with C5 in normal human plasma and doest not with plasma from patients deficient in C5, when tested in sandwich ELISA in combination with a polyclonal antibody against C5. Product Cat. No. 250302 reacts in Western blot with C5 in normal human plasma in nonreduced form only (PEG precipitated C5) and no reaction is seen with plasma from C5-deficient patients./p
pE: 1:8,000;/p
pWB: 1:500/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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