C-reactive Protein (CRP) (1-point-calibration) ELISA

C-reactive Protein (CRP) is mainly formed in hepatocytes. The synthesis rate of CRP is
influenced by the cytokines involved in the inflammatory processes. The biological
half-life time is estimated to be 13–16 hours. The serum CRP concentration reflects
very sensitive acute fever, pneumonia and myocardial infarction.
Studies describe an association between inflammatory reactions and cardiovascular
diseases like arteriosclerosis or latent and chronic persistent infections. As a marker
for inflammation, CRP high-sensitive can be used to predict the risk of myocardial
infarction and stroke.
The CRP determination in urine using the high sensitive ELISA method allows - together
with a2
-Macroglobulin - an early screening diagnose after kidney transplantations.
The CRP kit provides an easy to use assay for monitoring anti-rejection therapies.
ELISA was used for years to test hundreds of patients. Its predictive diagnostic
value was compared with the gold standard (kidney biopsy).