c-Myc Tag Antibody

Catalog Number

250608

Unit

0.1 mg

 

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Description

The Myc proto-oncogene protein (c-Myc) participates in the regulation of gene transcription. C-Myc is a transcription factor that binds DNA containing the core sequence 5'-CACGATG-3' but also in a non-specific manner. c-Myc activates genes related to cell growth. Overexpression of c-Myc is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC is a cause of a B-cell chronic lymphocytic leukemia. This antibody recognizes the C-term c-Myc peptide (EQKLISEEDL) used to express c-Myc-tagged fusion proteins.

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Alternate Names

c-Myc; Myc proto-oncogene protein; transcription factor p64; MYC; Myc Tag; C-Myc Tag

Accession No.

P01106

 

Clonality

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human c-Myc.

Application Notes

E: 1:500-1:1,000

WB: 1:200-1:500

IHC: 1:200-1:500

Reacts with  :H

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.