c-Jun Antibody

貨號 Cat. No.
3702-100
規格 Size
100 µg

Description

pstrongAntibody Target: /strongc-Jun/p
pbAlternative Name: /bJUN , AP1 , p39 , c-Jun/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen: /bRecombinant human c-Jun (1-79)-GST fution protein/p
pbAccession#: /bAAH09874/p
pbGene ID: /b3725/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) affinity purified rabbit anti-c-Jun polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhuman, mouse, rat/p
pbApplication: /bWestern blot, Immunohistochemistry/p
pbApplication amp; Usage: /bWestern blotting (0.5-2 micro;g/ml) and Immunohistochemistry (20-40 micro;g/ml). However, the optimal conditions should be determined individually. The antibody only recognizes c-Jun, and will not detect the endogenous levels of Jun B or Jun D./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping: /bgel pack/p
pbShelf Life: /b12 months/p
pbBackground Descriptions: /bExtracellular stimuli such as growth factors and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation at Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. JNK (c-Jun N-terminal Kinase) binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. The activity of JNK is stimulated by the same signals that activate c-Jun./p

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