c-FLIP Antibody

貨號 Cat. No.
3058-100
規格 Size
100 µg

Description

pstrongAntibody Target :/strongFLIP/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bSynthetic peptide near the C-terminus of human FLIPa/FLIPL form/p
pbAccession#: /bO15519/p
pbGene ID: /b8837/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.2 mg/ml/p
pbFormulation: /b100 micro;g (0.2 mg/ml) affinity purified rabbit anti-FLIP polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/ms/rt/p
pbApplication: /bWB/IF/p
pbApplication amp; Usage: /bWestern blot analysis (0.5-4 micro;g/ml) and immunofluorescence. However, the optimal conditions should be determined individually. The immunoaffinity-purified antibody detects 58 kDa FLIPL on SDS-PAGE immunoblots, in samples from human, mouse and rat origins. The antibody recognizes only the FLIPL form./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bc-FLIP was cloned by several labs independently and termed Casper, I-FLICE, FLAME-1, CASH AND CLARP. c-FLIP contains two death effector domains and has sequence homology to caspase-8. c-FLIP interacts with adapter protein FADD and caspaser-8 and -10, and potently inhibits apoptosis induced by all known death receptors. Two splice variants of c-FLIP have been identified and termed FLIPl and FLIPs/p

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