Bonzo/STRL33 Polyclonal Antibody
- 貨號 Cat. No.
- 5001-100
- 規格 Size
- 100 ug
Description
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pbHOST:/b Rabbit/p
pbIMMUNOGEN:/b Synthetic peptide corresponding to residues around amino acids 14 of human BONZO/STRL33./p
pbFORMULATION:/b 100 ug (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal./p
pbSPECIES REACTIVITY:/b human/p
pbSTORAGE CONDITIONS:/b Store at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND:/b Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor (1-4). Bonzo/STRL33 serves as coreceptor for SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes./p
pbSPECIFICITY:/b The antibody recognizes a ~40 kDa Bonzo in human spleen tissue lysate./p
pbAPPLICATION:/b The antibody can be used in Western blotting (1-4 ug/ml), However, the optimal concentrations should be determined individually./p
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pbHOST:/b Rabbit/p
pbIMMUNOGEN:/b Synthetic peptide corresponding to residues around amino acids 14 of human BONZO/STRL33./p
pbFORMULATION:/b 100 ug (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal./p
pbSPECIES REACTIVITY:/b human/p
pbSTORAGE CONDITIONS:/b Store at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND:/b Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor (1-4). Bonzo/STRL33 serves as coreceptor for SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes./p
pbSPECIFICITY:/b The antibody recognizes a ~40 kDa Bonzo in human spleen tissue lysate./p
pbAPPLICATION:/b The antibody can be used in Western blotting (1-4 ug/ml), However, the optimal concentrations should be determined individually./p
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