BoneTRAP® (TRAcP 5b) ELISA

For the quantitative determination of the active isoform 5b of tartrate-resistant acid phosphatase (TRACP). The BoneTRAP® (TRAcP 5b) ELISA assay is a specific method to detect TRACP 5b activity freshly liberated from osteoclasts. It is intended for use as an indicator of bone resorption and can be used as an aid in monitoring bone resorption changes in post-menopausal women and individuals diagnosed with osteoporosis undergoing anti-resorptive therapies.

In-vitro, TRACP 5b activity reflects the number of osteoclasts and therefore the BoneTRAP® (TRAcP 5b) ELISA Assay can be conveniently used to determine osteoclast number in human osteoclast cultures.