BMPR1A Peptide

h1 class=titleBMPR1A Peptide/h1
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h4Catalog Number/h4
pstrong350513/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4Price/h4
pstrong$50.00/strong/p
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h4Description/h4
pUpon ligand binding, BMPR1A forms a receptor complex consisting of two type II and two type I transmembrane Ser/Thr kinases. The type I receptors are activated by the type II receptors by using a phosphorylation mechanism, and subsequently bind SMAD transcriptional regulators. Defects in BMPR1A are the cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2, which lead to gastrointestinal, breast, thyroid, endometrial and colon cancers./p
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h4Format/h4
pnbsp;/p
pEach vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect./p
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h4Data and Images/h4
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h4Product Citations/h4
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h4Recommended Products/h4
pbr /
a href=http://abbiotec.com/antibodies/bmpr1a-antibody200151 BMPR1A Antibody/abr /
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h4Alternate Names/h4
pBone morphogenetic protein receptor type IA; Serine/threonine-protein kinase receptor R5; SKR5; Activin receptor-like kinase 3; ALK-3; CD292 antigen; BMPR1A; ACVRLK3/p
h4Accession No./h4
pa class=accession-link href=http://www.expasy.org/uniprot/P36894 target=_blankP36894/abr /
a class=accession-link href=http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=proteinamp;id=41349437 target=_blankNP_004320/abr /
nbsp;/p
h4MW/h4
p1936 g/mol/p
h4Sequence/h4
pThe synthetic peptide used to raise the antibody Cat. No. 200151 is selected from a sequence within the N-term region of human BMPR1A. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended./p
h4Composition/h4
pnbsp;/p
pC77H126N22O34S1/p
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h4Purity/h4
pPurity gt; 80% by HPLC/p
h4Solubility/h4
pDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile./p
h4Storage/h4
pStore at -20deg;C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20deg;C./p
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