BMP-7, human recombinant

Alternate Names / Synonyms: Osteogenic Protein 1, BMP-7

Gene Symbol: BMP 7

Accession #: P18075

Gene ID: 655

Gene Source: Human

Recombinant Host: E. coli

Appearance: Lyophilized protein

Physical Form: Sterile filtered and lyophilized with no additives

Molecular Weight: 15.7 kDa

Purity by SDS-PAGE: ≥98%

Purity by HPLC: ≥98%

Endotoxin Level: <0.1 ng/μg

Biological Activity: BioVision’s recombinant human BMP-7 is biologically active. The EDâ‚…â‚€ as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.

Reconstitution: Reconstitute to a concentration of 0.1-1.0 mg/ml in water. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Storage Temp.: -20°C

Shipping: Gel pack

Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-7 produced from E. coli is a 15.7 kDa monomeric, non-glycosylated, polypeptide chain containing 139 amino acid residues.

Handling: Centrifuge the vial prior to opening.