BMP-4, human recombinant

Alternate Names / Synonyms: BMP4, ZYME, BMP2B, BMP2B1

Gene Symbol: BMP 4

Accession #: P12644

Gene ID: 652

Gene Source: Human

Recombinant Host: E. coli

Appearance: Lyophilized protein

Physical Form: Sterile filtered and lyophilized powder

Molecular Weight: 13.0 kDa

Purity by SDS-PAGE: ≥98%

Purity by HPLC: ≥98%

Endotoxin Level: <0.1 ng/μg

Biological Activity: BioVision’s recombinant human BMP-4 is biologically active. The EDâ‚…â‚€ as determined by dose-dependent induction of alkaline phosphatase activity with C2C12 cells is in the range of 2-12 µg/ml.

Reconstitution: Reconstitute to a concentration of 0.1-1.0 mg/ml in sterile 20 mM acetic acid. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Storage Temp.: -20°C

Shipping: Gel pack

Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-4 produced from E. coli is a 13 kDa monomeric, non-glycosylated, polypeptide chain containing 116 amino acid residues.

Handling: Centrifuge the vial prior to opening