BK channel Antibody

貨號 Cat. No.
251351
規格 Size
0.1 mg
品牌 Brand
Abbiotec

Description

BK Channel (N-term) Antibody
Rabbit Polyclonal











Catalog Number


251351


Unit


0.1 mg


Isotype


Rabbit Ig

Applications


E, WB, IHC

Species reactivity


H, M, R, Other

Format


 


Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.


 



Description


The BK channel (calcium-activated potassium channel subunit alpha-1 or KCNMA1) is a potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). BK channel is also activated by the concentration of cytosolic Mg(2+). BK channel has a key role in controlling excitability in a numerous systems, such as smooth muscle contraction, tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. Defects in KCNMA1 are the cause of generalized epilepsy and paroxysmal dyskinesia (GEPD).




Recommended Products




250561 BK Channel Antibody

 


Alternate Names


Calcium-activated potassium channel subunit alpha-1; Calcium-activated potassium channel, subfamily M subunit alpha-1; Maxi K channel; MaxiK; BK channel; K(VCA)alpha; BKCa channel; BKCA alpha; KCa1.1; Slowpoke homolog; slo homolog; Slo-alpha; Slo1; hSlo; KCNMA1; KCNMA; SLO


Accession No.


Q12791

 


Antigen


 


KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human BK Channel.


 


Application Notes


 


E: 1:500-1:1,000

WB: 1:100-1:500

IHC: 1:100-1:500


 


Storage


 


Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.





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