Biotinylated Human LILRA5 / CD85f / ILT11 Protein, His,Avitag™

Source : 

Biotinylated Human LILRA5, His,Avitag (LI5-H82E1) is expressed from human 293 cells (HEK293). It contains AA Gly 42 - Arg 268 (Accession # A6NI73-1).

 

Molecule : LILRA5

 

Synonyms : LILRA5,CD85f,ILT11,LIR9,LILRB7

 

Format : Powder

 

Category : MABSol® Biotin Labeled Proteins

 

Accession : NP_871714.1

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 28.9 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 28.9 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

LIRs are immunoglobulin-like receptors that have activating and inhibitory functions in leukocytes. Leukocyte immunoglobulin-like receptor A5 (LILRA5) belongs to a family of receptors known to regulate leukocyte activation. LILRA5, expressed as a membrane-bound receptor and as a secreted molecule. The transmembrane LILRA5 contain a short cytoplasmic domain and a charged arginine residue within the transmembrane region that is likely to mediate its association with another coreceptor. LILRA5 is mostly expressed in myeloid cells, including monocytes and neutrophils.

 

References :

(1) Shiroishi M., et al., 2006, J. Biol. Chem. 281:19536-19544.
(2) Mitchell A., et al., 2008, Eur. J. Immunol. 38:3459-3473.
(3) Borges L., et al., 2003, Blood. 101:1484-1486.