Biotinylated Human LILRA2 / CD85h / ILT1 Protein, His,Avitag?
- 貨號 Cat. No.
- LI2-H82E9
- 規格 Size
- 200ug
- 品牌 Brand
- ACROBiosystems
- Species
- Human
- Conjugate
- Precision Avi
- Expression System
- HEK293
- Tag
- His Tag & Avi Tag
Description
LILRA2 (Leukocyte immunoglobulin like receptor A2), also known as CD85H and LIR7 (Leukocyte immunoglobulin-like receptor 7). It belongs to the subfamily A class of LIR receptors (LILRAs), which are single-pass type I transmembrane proteins with 2-4 extracellular Ig-like domains, a transmembrane domain (TM), and a short cytoplasmic tail. LILRA2 contains 4 Ig-like C2 type domains in the extracellular region. LILRA2 does not bind class I MHC antigens. LILRA2 is expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. LILRA2 is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response.

