Biotinylated Human LILRA1 / CD85i / LIR-6 Protein, His,Avitag™

Source : 

Biotinylated Human LILRA1, His,Avitag (LI1-H82E8) is expressed from human 293 cells (HEK293). It contains AA Pro 17 - Asn 461 (Accession # O75019-1).

 

Molecule : LILRA1

 

Synonyms : LILRA1,LIR6,CD85i,LIR-6

 

Format : Powder

 

Category : MABSol® Biotin Labeled Proteins

 

Accession : NP 006854.1

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 52.2 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 52.2 kDa. The protein migrates as 60-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Leukocyte immunoglobulin-like receptors (LILRs) are inhibitory, stimulatory or soluble receptors encoded within the leukocyte receptor complex. Some LILRs are extensively polymorphic, and exhibit evidence for balancing selection and association with disease susceptibility. LILRA1 (LIR-6) can recognize MHC (major histocompatibility complex) class I or class I-like molecules, and high levels of sequence similarity among LILRA1, LILRA2 (ILT1), LILRA3 (ILT6) and LILRB1/B2.

 

References :

(1) Chen Y., et al., 2009, J. Mol. Biol. 386:841-853.
(2) Mamegano K., et al., 2008, Genes. Immun. 9:214-223.